| 8:00 a.m. |
Breakfast |
| 9:00 a.m. |
Welcome Back |
| 9:05 a.m. |
Future of the Brain: Neurology
Advances in understanding the brain have led to powerful new approaches for managing neurological disorders over the past decade. Hear from Dr. S. Andrew Josephson, chair of UCSF's Department of Neurology, about how the next decade will be even more exciting. Dr. S. Andrew Josephson will dicuss how new treatments will emerge for a diverse set of neurological problems that affect patients of all ages, including stroke, epilepsy, movement disorders, and neurodegenerative diseases.
Speaker:
S. Andrew Josephson, MD, Neurology
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| 9:15 a.m. |
Building a Resilient Brain
The science of resilience is here. How does early life experience influence our physiology? Could a single protein called klotho block dementia and insulate our brains against diseases of aging? How does chronic stress affect the brain, heart, and immune health? Experts share what’s behind chronic stress, how to build stress resilience, and how both are connected to healthy development and aging.
Speakers:
Nicki Bush, PhD, Psychiatry and Behavioral Sciences
Dena Dubal, MD, PhD, Neurology
Elissa Epel, PhD, Psychiatry and Behavioral Sciences
Moderator: Alice Park, Senior Correspondent, TIME
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| 9:35 a.m. |
Understanding Sleep: Benefiting Brain Health and Beyond
Consider this: The human body can actually survive longer without food than it can without sleep. Leading experts will share new research on just how essential sleep is for our survival and for our brains. We’ll learn how sleep interacts with mood and how it regulates the immune system and our ability to fight infections. We’ll also explore how sleep impacts and modulates neurologic conditions, including neurodegenerative diseases. Could sleep hold the key to preventing, treating, or decreasing the risk for Alzheimer’s and Parksinon’s? A deep dive into the benefits of better sleep for your brain.
Speakers:
Liza Ashbrook, MD, Neurology
Ying-Hui Fu, PhD, Neurology
Aric Prather, PhD, Psychiatry and Behavioral Sciences
Moderator: Liz Neeley, Founder and CEO, Liminal
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| 9:55 a.m. |
Discovering Causes, Developing Cures and Focusing on Prevention: The Future of Alzheimer’s and Neurodegenerative Disorders
It’s been called a dementia epidemic: More than 6 million Americans are living with Alzheimer’s disease today, with that number expected to reach 13 million by 2050. While there is still not a single medicine that halts or slows any neurodegenerative diseases, there is hope. Leading researchers from UCSF share the latest science, diagnostics, and strategies that might prevent and treat Alzheimer’s and other devastating neurodegenerative diseases.
Speakers:
Bruce Miller, MD, Neurology
Lennart Mucke, MD, Neurology and Gladstone Institute of Neurologic Disease
Kristine Yaffe, MD, Psychiatry and Behavioral Sciences
Moderator: S. Andrew Josephson, MD, Neurology
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| 10:15 a.m. |
Unconventional Treatment: Using Technology to Improve Brain Health
Social media, video games, apps. They’re a daily and constant concern plaguing millions of parents. But what if some of these technologies could actually be used to advance brain health equity for children? We’ll hear from faculty who are developing to use technology for good, including through the creation of the first FDA-approved video game to treat ADHD, the first school-based video-delivered ADHD treatment in Latin America and the first mental health treatment app designed by and for foster care youth. A fresh look at technology and our children.
Speakers:
Adam Gazzaley, MD, PhD, Neurology
Lauren Haack, PhD, MS, Psychiatry and Behavioral Sciences
Marina Tolou-Shams, PhD, Psychiatry and Behavioral Sciences
Moderator: Olga Khazan, Staff Writer, The Atlantic
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| 10:35 a.m. |
Break
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| 10:55 a.m. |
Precision Medicine for Brain Injury: How Big Data Can Enhance Recovery
Traumatic brain injuries – stemming from falls, sports injuries, car accidents and combat-related injuries – are a major cause of death and disability in the US and can affect people of all ages. Consequences of traumatic brain injury are unique from one patient to the next. Some injuries, like concussions, are paradoxically classified as “mild” despite debilitating symptoms when brain scans and other tests have normal results. A UCSF trauma neurosurgeon joins us to share the latest information about precision medicine for brain injury. How are leading scientists at UCSF using big data to enhance recovery? We’ll also learn about the potential for a new blood test for concussions, along with the future of diagnosing and treating head injuries from all causes.
Speaker:
Geoffrey Manley, MD, PhD, Neurological Surgery
Moderator: Cathra Halabi, MD, Neurology
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| 11:05 a.m. |
Recreating Brain Circuits
For many patients suffering from a traumatic brain injury, too much damage to brain circuits exists for any chance of recovery. But hope is on the horizon thanks to the pioneering work of UCSF scientists who are aiming to recreate brain circuits and then integrate them into the injured brain. We’ll hear from one leader in the field about how this new method might even augment brain capacity in normal brains. A revealing look at the next generation of brain circuitry.
Speaker:
Karunesh Ganguly, MD, PhD, Neurology
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| 11:10 a.m. |
The Future of the Neurosurgery Operating Room
The future is here. UCSF is already using state-of-the-art tools that eventually will be commonplace in neurosurgery operating rooms everywhere. Technologies currently at the fingertips of UCSF neurosurgeons include everything from robots that assist doctors in performing brain surgery to laser sensors that create 3-D maps of the brain. In the near future, new surgeries will not involve even a single incision. Take a fron- row seat and learn from UCSF neurosurgeons about the promise of these technologies and how they can improve patient outcomes after surgery in an extraordinarily complex environment: the human brain.
Ezequiel "Eze" Goldschmidt, MD, PhD, Neurological Surgery
Doris Wang, MD, PhD, Neurological Surgery
Moderator: Edward Chang, MD, Neurological Surgery
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| 11:25 a.m. |
Future of the Brain: Psychiatry
Historically , psychiatry has remained on the sidelines while technological and scientific advances transformed the fields of neurology and neurosurgery. UCSF’s Dr. Matthew State, an internationally-renowned molecular geneticist and child psychiatrist, will describe how emerging biological therapies are now taking on these most mysterious and complex brain disorders. From gene-focused therapies and mapping the cellular proteome in autism to harnessing molecular mechanisms of drug action in depression and PTSD, psychiatry is emerging as a full partner in the biological revolution.
Speaker:
Matthew State, MD, PhD, Psychiatry and Behavioral Sciences
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| 11:35 a.m. |
Decoding Autism: The Search for Novel Treatments
There’s no single cause of autism spectrum disorders (ASD), but researchers have pinpointed more than 100 genes underlying the condition. The key question: Where do we go from here? What comes next in ASD therapeutics development? Join us for an exceptional conversation with some of the pioneers in the field.
Speaker:
Stephan Sanders, MBBS, PhD, Psychiatry and Behavioral Sciences
Moderator: Jonathan Wosen, West Coast biotech & life sciences reporter, STAT News
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| 11:50 p.m. |
Community Psychiatry: Moving Mental Health from the Margins to the Center
The homeless crisis in the Bay Area is intertwined with a mental health crisis. Consider this: Approximately 30,000 unhoused persons in nine Bay Area counties, a number that continues to skyrocket during the pandemic. In addition, while nearly half of homeless individuals reported psychiatric or emotional problems, only a fraction of them receive mental health services. Leaders from UCSF are on the front lines of these twin epidemics of suffering on society's margins. How do public psychiatrists engage with communities on the margins to promote brain health equity? We will hear how experts are using technological innovation and science to support and collaboratively create solutions with our most vulnerable neighbors.
Speakers:
Lisa Fortuna, MD, MPH, Psychiatry and Behavioral Sciences
Fumi Mitsuishi, MD, MS, Psychiatry and Behavioral Sciences
Moderator: Olga Khazan, Staff Writer, The Atlantic
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| 12:05 p.m. |
Day 2 Closing Remarks
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| 12:10 p.m. |
Transfer to Lunch
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| 12:30 p.m. |
Closing Luncheon
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| 1:05 p.m. |
Nobel Dialogue: Driving Innovation
With six Nobel laureates, it’s no secret why UCSF is regarded as one of the world’s leading medical and life science universities. We’ll take this rare opportunity to sit down with a panel of Nobel Prize winners for a conversation you won’t hear anywhere else. What drives innovation? What is the future of neuroscience? And, at a time when science in general is being challenged, where do the brightest minds see cause for hope?
Speakers:
Elizabeth Blackburn, PhD, FRS, AC, Biochemistry and Biophysics
Jennifer Doudna, PhD, Molecular and Cell Biology and Chemistry, University of California, Berkeley
David Julius, PhD, Physiology
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| 1:45 p.m. |
Program Concludes
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| 2:15 p.m. |
Summit Concludes |
